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The Amazing Spider-Man (1963) #361 - Comic Book DB
Part 1: Cletus Kasady is not himself. He's become Carnage, a lifeform not unlike Venom....and he's going on a killing spree. Spiderman locates Carnage and they fight. However Carnage get's the upper hand, seriously injuring Spiderman and escapes. Realizing how powerful Carnage is, and with other superhero groups unavailable, Spiderman turns to one of his powerful enemies for assistance.